Nwogoh Benedict

Ag. Head of Department

DEPARTMENT OF HAEMATOLOGY

Background

The Department of Haematology and Blood Transfusion was established in 1979, from the hitherto Department of Pathology which comprised the four subunits: Haematology, Medical Microbiology, Chemical Pathology and Morbid Anatomy. Since its establishment, the department has been headed by the following:

  Name Duration in Office
1. Prof. N.O. Osamo 1973-1979
2. Dr. L.A. Okafor 1979-1990
3. Prof. A.A. Famodu Coordinator 1991
4. Dr. N.K.D. Halim 1992-1997
5. Dr. M.E. Enosolease 1998-1999
6. Dr. N.K.D. Halim 1999-2002
7. Dr. (Mrs.) O.A. Awodu 2002-2004
8. Dr. N.K.D. Halim 2004-2006
9. Dr. M.E. Enosolease 2006-2008
10. Prof. C.E. Omoti 2008-2010
11. Prof. O.A. Awodu 2010-2012
12. Assoc. Prof. G.N. Bazuaye 2012-Feb.2015
13. Prof. C.E. Omoti Feb. 2015-June,2015
14. Prof. N.K.D. Halim July, 2015  – May 2018
15 Prof C.E. Omoti June 2018 – June 2019
16 Dr. Nwogoh Benedict July 2019 till date

Philosophy and Objectives

Our objectives are to:

  • Provide high quality and simplified medical education (in haematology) to undergraduate medical students.
  • Provide appropriate and adequate practical exposure in haematology to undergraduate medical students.
  • Train medical undergraduates on the correct interpretation and clinical application of haematology investigation results.

 Our Vision

  • Our vision is to be a leader in terms of academic excellence in haematology researches and in the training of medical undergraduates on basic and professional knowledge and competence in the provision of care for patients with blood and blood related disorders.

 

 

Our Mission

  • Our mission is to produce medical graduates with sound knowledge and competence in haematology laboratory diagnostics, clinical care of patients with blood and blood related disorders.

 

Faculty

  Name Status Qualifications URL link to Google Scholar account
1 Halim NKD Professor MB.BCH, FMCPath,

Cert. Haematology (London),

Cert. Virology (Baltimore).

https://scholar.google.com/citations?hl=en&user=2NKiJlkAAAAJ
2 Enosolease ME Professor MB.BS, FMCPath https://scholar.google.com/citations?hl=en&user=HMNrIDUAAAAJ
3 Awodu OA Professor MB.BCH, FMCPath. https://scholar.google.com/citations?hl=en&user=mZbhiZEAAAAJ
4 Omoti CE Professor MB.BS, FMCPath https://scholar.google.com/citations?hl=en&user=QQ-kP1EAAAAJ
5 Bazuaye GN Professor MB.BS, FMCPath,

Cert. Stem Cell Transplant (Basel).

6 Nwogoh B Senior Lecturer MB.BS, FMCPath, FWACP,

MSHS D&I Science (Baltimore)

https://scholar.google.com/citations?user=KXikat4AAAAJ

 

Technical Staffs

  Name Status
1. Mr. AJP. Kamdem Chief Medical Lab. Scientist
2. Mrs. J Otikor Principal Med Lab. Scientist
3. Mrs. EL Ighalo Med Lab. Scientist 1

 

 

Courses

Course code Description
HBT 302 Haematology I: Introduction
Blood cells and blood forming organs

Bone marrow structure and function

Haemopoiesis

Ineffective haemopoiesis

Haemoglobin: structure, function, synthesis and breakdown (haemolysis)

Physiological adaptation to anemia: role of 2,3 diphosphoglycerate (DPG).

Factors affecting oxygen dissociation curve.

Normal haematological values

Disparity in some blood counts in normal Nigerians and other black people in relation to Caucasians (whites) (total WBC count, relative neutropenia and eosinophilia).

Definitions and classification of anaemia I.

Polycythemia: definition (including by RBC mass). Primary and secondary.

Abnormal RBC morphology in anaemia.

Systematic plan for the diagnosis of anaemia.

Indication for bone marrow aspiration and biopsy

Quality assurance in haematology

HBT 427 General Haematology II: Anaemia
Definition and classification of anaemia II

Microcytic anaemia: Iron deficiency, lead poisoning, thalassemia and anaemia of chronic disorders.

Macrocytic anaemia:

·       Megaloblastic anaemia: Folic acid deficiency, vitamin B12 (including Pernicious anaemia).

Anaemia due to bone marrow failure:

·       Myelophthisic anaemia, Aplastic anaemia.

Haemolytic anaemia: due to haemoglobin disorders

·       Sickle cell disorders, sickle cell trait and sickle cell disease; “balanced polymorphism and Sickle cell gene”. Other haemoglobin variants that coexist with sickle cell haemoglobin (Hb-C, Hb-D, Hb-E etc.

·       Other rare abnormal haemoglobin: Unstable haemoglobinopathies: Methaemoglobinaemia and sulfhaemoglobinemia.

Haemolytic anaemia due to RBC enzyme deficiencies:

·       Glucose 6 phosphate dehydrogenase (G6PD) deficiency Protection of G6PD deficiency against malaria. Lyonization theory.

·       Pyruvate kinase deficiency and other RBC enzyme deficiencies.

RBC membrane disorders

·       Spherocytosis and elliptocytosis

Acquired haemolytic anaemia

·       Immune haemolytic anaemia due to antibodies (idiopathic, Evans syndrome, cold agglutinin antibodies, paroxysmal cold haemoglobinuria (PCH) and drug-induced immune haemolytic anaemia. due to defects in RBC membrane (including hereditary).

·       Microangiopathic haemolytic anaemia, prosthesis (cardiac) march haemoglobinuria.

·       Haemolytic anaemia due to parasitic infections (malaria), bacterial pathogens etc

HBT 517 Haematology: Blood Transfusion Medicine
Blood group systems: RBC antigens and antibodies

·       ABO blood group system

·       Rhesus blood group system

Blood donor selection and recruitment

·       Types of blood donor

·       Donor eligibility criteria

Blood bank serology

·       Blood grouping: cells and serum grouping, methods of blood grouping

·       Blood crossmatch

·       Antibody screening test: Direct and indirect Coomb’s (antiglobulin) test

Blood transfusion and transfusion reactions including transfusion transmissible infections.

Blood and blood component therapy

·       Preparation and indications for use

·       Rationale blood use

Haemolytic disease of the newborn.

HBT 527 White blood cell disorders
Benign disorders of WBC:

·       Leukopenia

·       Leukocytosis and leukemoid reaction: neutrophilia, lymphocytosis, eosinophilia (including tropical eosinophilia, hypereosinophilic syndrome

·       Diagnostic approach to lymphadenopathy

·       Infectious mononucleosis

·       Acquired immunodeficiency syndrome: HIV/AIDS

·       Structure and function of spleen

·       Disorders of the spleen: Hyposplenism, splenomegaly (including differentials of massive splenomegaly), hypersplenism.

o  Tropical splenomegaly syndrome

Molecular basis of cancers

Diagnostic methods in haematology: Morphology, immunophenotyping, cytogenetics, fluorescent in-situ hybridization and molecular methods.

Haematological malignancies:

·       acute leukaemia (myeloid and lymphoid): definition, epidemiology, aetiology, classification, clinical features, diagnosis, treatment and prognosis.

·       Chronic leukaemia: chronic lymphoid leukaemia, chronic myeloid leukaemia

·       Lymphoma:

o  Non-Hodgkin’s lymphoma: aetiology, classification, epidemiology, clinical features, diagnosis, staging, treatment and prognosis. Burkitt lymphoma, diffuse large B cell lymphoma, mycosis fungoides

o  Hodgkins lymphoma: aetiology, histologic types, epidemiology, clinical features, diagnosis, staging, treatment and prognosis.

·       Myeloproliferative disorders: Polycythaemia rubra vera, essential thrombocythaemia, idiopathic myelofibrosis.

·       Myelodysplastic syndrome (MDS)

·       Plasma cells dyscrasia including multiple myeloma.

·       Haemopoetic stem cell transplantation: introduction, types, conditioning, complications and management of HSCT

·       Human leukocyte antigen (HLA).

HBT 528 Bleeding disorders and Thrombosis
Haemostasis

Bleeding disorders due to platelets: qualitative and quantitative disorders

Thrombocytopenia: differentials, clinical features, investigation and treatment

Congenital and acquired defects of platelet function

Test for platelet function

Bleeding due to coagulation disorders: genetic (haemophilia, von Willebrand disease) and acquired disorders

Coagulation test: Prothrombin time, Activated Partial Thromboplastin Time, Thrombin time

Defibrination syndrome: Disseminated intravascular coagulopathy (DIC)

Thrombotic disorders

Anticoagulant therapy: heparin, Coumarin, DOACS

Inhibitors and potentiators of anticoagulant

Monitoring of Warfarin therapy: International standardization index (ISI) and international normalized ratio (INR).

HBT 518 Practical Haematology
Stains in haematology

Blood film preparation: principles and method of staining.

Identification of common haematologic disorders on peripheral blood films and bone marrow films.

Full blood count – PCV, WBC, platelets.

Hb electrophoresis

Serological tests – blood grouping and crossmatch, Coombs test

Coagulation test – prothrombin time, APTT and correction test; ISI and INR calculation and interpretation.